TEST

SPECIFICTIONS

Description

Colorless or light yellow oil

Identification

According to the requirements

Optical rotation（365nm）

+52.0°~+58.0°

Water content

≤1.0%

Travoprost related compound A

≤0.2%

Epoxide derivative

≤0.4%

15-epi Diastereomer

≤0.1%

5,6-trans Isomer

≤3.5%

15-Keto derivative

≤0.3%

Any other individual impurity

≤0.1%

Total impurities

≤4.0%

  Residue solvents

Acetone≤0.5%

Methanol≤0.3%

Toluene≤0.089%

Tetrahydrofuran≤0.072%

Ethyl acetate≤0.5%

Dichloromethane≤0.06%

Assay

96%~102%

Conclusion:

Complies with USP standards